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Sedation for EEG using clonidine

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For sedated EEG in children or other neurophysiology procedures, clonidine is the preferred agent as it is an effective sedative that does not alter the EEG recording, has a shorter duration of sedation than chloral hydrate with prompt recovery after sedation, and can be given in small oral volumes.

Clonidine Dosage for Sedation

Weight of Child Clonidine Dosage
<10 kg 0.05 mg (=50 micrograms)
10-30kg 0.1 mg (=100 micrograms)
>30 kg 0.15-0.2 mg (=150-200 micrograms)
In New Zealand clonidine is available in 25 microgram and 150 microgram tablets


EEG sedation for children with autism, Mehta, Patel & Castello. J Dev Behav Pediatr 25:102-104, 2004

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Document Control

  • Date last published: 16 March 2017
  • Document type: Clinical Guideline
  • Services responsible: Paediatric Neurology
  • Author(s): Melinda Nolan
  • Owner: Melinda Nolan
  • Editor: Greg Williams
  • Review frequency: 2 years

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