Menu Search Donate
Guideline identity image

Immunodeficiency - basic tests

This document is only valid for the day on which it is accessed. Please read our disclaimer.

Immune deficiency may present with recurrent infections but the initial presentation can also be with a severe infection which may be fatal. If an infant or young child presents with a life threatening infection and death is imminent/likely, consideration should be given to a limited immune screen.

Suggested investigations in seriously ill/dying infants and young children in whom underlying immune deficiency is possible are listed below.

Table 1: tests and sample requirements

Test for Sample required
Blood count EDTA 250uL
Serum IgG, IgA, IgM and IgE Serum 500uL
HIV serology Serum 500uL
Lymphocyte phenotype Heparin 500uL
TREC (in infants under 12 months) EDTA 500uL
DHR (replaces previous NBT) EDTA 500uL

Did you find this information helpful?

Document Control

  • Date last published: 24 August 2012
  • Document type: Clinical Guideline
  • Services responsible: Paediatric Intensive Care Unit
  • Owner: Fiona Miles
  • Editor: John Beca
  • Review frequency: 2 years