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Drug dosage identifier

Dextrose Gel

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Dose and administration

40% (40g/100ml) Dextrose Gel

Indications

Neonatal Hypoglycaemia

Criteria

  • Blood glucose concentration <2.6 mmol/L, but ≥ 1.2 mmol/L on first administration and ≥ 2.0 mmol/L on subsequent doses AND
  • ≥ 35 weeks' gestational age AND
  • < 48 hours after birth

Dose

  • 200 mg/kg (0.5 ml/kg)
  • Treat one episode of hypoglycaemia with a maximum of 3 doses of dextrose gel
  • Maximum of 6 doses of dextrose gel per baby in 48 hours

Administration

  • Dry inside of buccal mucosa with gauze
  • Apply dextrose to a gloved finger, and then massage into buccal mucosa
  • Offer baby a breast feed

References

  1. Harris DL, Weston PJ, Signal M, Chase JG, Harding JE. Dextrose gel for neonatal hypoglycaemia (the Sugar Babies Study): a randomised, double-blind, placebo-controlled trial. Lancet. 2013;382:2077-83. 
  2. Weston PJ, Harris D, Battin M, Brown J, Hegarty J, Harding JE. Oral dextrose gel for the treatment of hypoglycaemia in newborn infants (Protocol). Cochrane Database Syst Rev. 2014; Issue 
  3. Art. No.: CD011027. DOI: 10.1002/14651858.CD011027.

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Document Control

  • Date last published: 31 December 2014
  • Document type: Drug Dosage Guideline
  • Services responsible: Neonatology
  • Editor: Sarah Bellhouse
  • Review frequency: 2 years