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- Hypospadias is a very common congenital anomaly (1 in 300 male births). It is most often an isolated finding but may be associated with other abnormalities.1
- The incidence is increased if first degree relatives are affected. Up to 26% of male offspring of an affected father may have hypospadias, and the risk in subsequent siblings is 12%.2
- It is more common in male infants who are growth restricted and premature. Other risk factors include parental subfertility.3
Definition and description
Hypospadias (hypo = below; spadon = a fissure or a 'hole') is a ventral displacement of the urethral meatus and may be associated with:
- Incomplete formation of the prepuce / foreskin (dorsal 'hooding')
- Ventral curvature (chordee).
Urethral meatal openings are generally described as being:
- Anterior - where the meatus is near the tip of the penis
- Middle - where the meatus is along the shaft of the penis
- Posterior - where the meatus is near the base of the penis or in the scrotum
Early recognition and paediatric urological referral is useful for counselling and planning timing of surgery
The baby requires a complete examination to determine whether other external abnormalities are present.
- Penile length should be determined
- Normal stretched penile length at term >2.5cm
- If penile length <2.5cm, refer to the Paediatric Endocrinology service for assessment. Testosterone may be indicated.
- Renal ultrasound is not indicated for simple anterior or middle
hypospadias unless there are other features of concern (for
example, dysmorphic features).
- Other conditions, such as an enlarged utricle, may be present particularly with posterior hypospadias
- Renal abnormalities are more common with more posterior hypospadias. Renal ultrasound is the investigation of choice initially.
- Posterior hypospadias - particularly in the absence of palpable gonads - should be regarded as an intersex disorder and investigated appropriately.
- Parents should be reassured that hypospadias is a common condition which can be corrected with surgery.
- Surgery is performed by the Paediatric Urologists at Starship Children's Hospital.
- Surgery is usually undertaken between 6 and 18 months, although timing will depend on the surgeon and other factors. Often more than one procedure is required and it is preferable to complete all stages in early childhood.
- It is critical that parents are told that circumcision should not be performed as the foreskin remnant is required for surgical repair.
- The surgical principles are:
- To reposition the meatus on to the head of the penis (meatoplasty and glanduloplasty)
- To straighten the chordee (othoplasty)
- To correct the hooded foreskin (by circumcision)
- To achieve all of this with an aesthetically acceptable result
- Babies should be referred on discharge to the paediatric surgical service at Starship Children's Hospital.
- Send referrals to the Department of Paediatric Surgery - Fax 307 8952
- Alternatively, contact a paediatric urologist directly.
- Kulkarni BK, Oak SN, Patel MP, Merchant S, Borwankar SS. Developmental anomalies associated with hypospadias. J Postgrad Med 1991;37:140-3
- Bauer SB, Retik AB, Colodny AH. Genetic aspects of hypospadias. Urol Clin North Am 1981;8:559-64.
- Manson JM, Carr MC. Molecular Epidemiology of Hypospadias: Review of Genetic and Environmental Risk Factors. Birth Defects Research 2003;67(Part A):825- 36.
- Smith EP, Wacksman J. Evaluation of severe hypospadias. J Pediatr 1997;131:344-6.
- Shukla AR, Patel RP, Canning DA. Hypospadias. Urol Clin North Am 2004 Aug;31(3):445-60. (This entire issue is devoted to hypospadias)
- Anonymous. Timing of elective surgery on the genitalia of male children with particular reference to the risks, benefits and psychological effects of surgery and anesthesia. Pediatics 1996;97(4):590-4.
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- Date last published: 26 March 2015
- Document type: Clinical Guideline
- Services responsible: Neonatology
- Owner: Newborn Services Clinical Practice Committee
- Editor: Sarah Bellhouse
- Review frequency: 2 years
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