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Heparin monitoring

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For more detail please refer to the Neonatal Heparin Guideline or the Anticoagulation Guide for Therapeutic Heparin or Low Dose Heparin

APTT (seconds) Bolus (u/kg) Stop Infusion (min) % Infusion Rate Change Repeat APTT
<40 50 0 +10%  4-6 hours
40-49 0 0 +10% 4-6 hours 
50-80 0 0 Daily 
81-90 0 0 - 10%  4-6 hours 
91-115 0 30 - 10%  4-6 hours 
>115 0 60 - 15%  4-6 hours

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Document Control

  • Date last published: 01 December 2009
  • Document type: Clinical Guideline
  • Services responsible: Paediatric Haematology/Oncology
  • Author(s): Lochie Teague, Nyree Cole, George Chan
  • Editor: Greg Williams
  • Review frequency: 2 years

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